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Over the past century, many diseases that previously would have been fatal are now almost entirely curable. However, the prognosis and treatments for end-stage organ failure are still bleak.

Chronic diseases lead to wear and tear in organs such as the liver, lungs, kidneys, and more. Eventually, the damage builds up to a point where the organs stop working — at this point, patients currently have relatively few options. The current standard of care for patients with end-stage organ failure is an organ transplant. However, the demand for a transplant greatly exceeds the supply of organs.

When you check off…

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“Changing the world can happen anywhere, and anyone can do it.”

These words were spoken by Admiral William H. McRaven, United States Navy four-star admiral who served as the ninth commander of the United States Special Operations Command, during his 2014 commencement speech at the University of Texas at Austin. Admiral McRaven’s message was simple, yet profound and applies to so many aspects of our daily life.

Throughout history, there is a pattern that emerges over and over again: capital drives change. Wherever money is injected, innovation often follows. …

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The greatest global public health crisis in a century has put the life sciences industry in the spotlight. Called to center stage, the entire industry delivered on innovation and responsiveness. Many of the solutions, therapies, and treatment modalities brought forward, like telemedicine and mRNA vaccines were only available because their core technologies had been under development long before COVID-19.

While the pandemic is still underway, the recent experience of seeing future therapies become today’s treatments — and in the process building billion-dollar businesses — begs the question what does the future look like for healthcare? But before we dive into…

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While we are no means out of the woods, the FDA’s analysis this week of Johnson & Johnson’s COVID-19 single-dose vaccine is more good news that points to the gradual return to normal life. Throughout the crisis, the health care industry’s response to COVID 19 has been one of resilience, persistence, and commitment on the part of care providers and innovation and collaboration among researchers and developers. It has been a difficult time but was an amazing opportunity for every corner of the healthcare industry — from early and late-stage developers to front-line workers — to demonstrate that healthcare is…


No matter how much we yearn to recover our lost youth or the health that went along with it, every day brings us closer to death, the ultimate irritating limit. As Roman emperor Marcus Aurelius said, “do not act as if you were going to live ten thousand years. Death hangs over you.”

Image Source: When Did the Roman Empire Start and End?

Today, we’re living in a world where our understanding of biology has dramatically increased not only our collective lifespan, but also our healthspan. While Marcus Aurelius was wealthy on a scale beyond belief, he couldn’t escape the…

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Angel investing is all about spotting potential in teams and companies.

If you had invested $10,000 in Facebook’s seed round back in 2004, that money would be worth over $250 million today. The same goes for many other companies, where a seed investment would have made a 100x+ return.

You hear all these stories about investors getting in early on startups that blow up, but how does all of this work? In recent years, loosening government regulations and new investing platforms has made angel investing more accessible than ever.

Basics of Startup Investing

Angel investing gives individuals the opportunity to…

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You have probably heard time and time again to “diversify your portfolio” — this is to minimize overall risk and not put all your eggs in one basket. However, investing in early-stage startups, especially in healthcare, requires a slightly different approach.

Venture capital differs from many other forms of investing because 90% of startups fail. Instead of counting on each investment to generate a somewhat reliable return, VCs make money by having a small number of outlier companies generate 10x-100x+ returns that compensate for failures across the rest of the portfolio.

Thus, venture capital investing focuses more on the potential…

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Throughout history, there is a pattern that emerges over and over again: capital drives change. Wherever money is injected, innovation often follows.

You hold a great amount of power as an investor because of this — you have the ability to influence where the money is directed, which means where time and energy are spent. …

EnClear Therapies is developing device-based systems to reduce or stop the progression of neurodegenerative diseases by eliminating the toxic proteins known to drive the underlying pathology of disease. EnClear’s initial focus is on ALS (Amyotrophic Lateral Sclerosis) and related disease groups such as PSP (Progressive Supranuclear palsy).

ALS, also known as Amyotrophic Lateral Sclerosis or Lou Gehrig’s Disease, came into mainstream view in 2014 when the ice bucket challenge blew up the internet and attracted everyone from pop celebrities to Bill Gates to participate and raise money for awareness and research. In total, this challenge helped the ALS Association generate…

The desire to prolong life existed for centuries from finding the holy grail to controversial start-ups such as Ambrosia focusing on teen blood transfusions. No one has been quite able to crack the code to immortality, however, a rising biotech start-up is taking a huge step forward in this space by targeting what kills one out of every four Americans: heart disease. We are excited to announce our investment in Repair Biotechnologies, which aims to use novel technologies to address age-related diseases, and is starting out by tackling atherosclerosis. …

Bioverge, Inc.

Connecting the world to startups dedicated to transforming healthcare

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